When Señora Moreno learns of Ramona's love for Alessandro, she forbids the girl to marry. Ramona's strength, however, is greater than anyone expects, and she runs away with the handsome Indian. Through numerous hardships, including the death of her beloved Alessandro, Ramona's strength and love continue to grow. As one of the great ethical novels of the 19th century, Ramona was both a political and literary success and continues to move modern readers with its sympathetic characters and its depiction of the Native American's struggle in the early West. Ramona was immensely popular almost immediately upon its release, with over 15,000 copies sold in the ten months before Jackson's death in 1885. Just a year later in 1886, the North American Review called it "unquestionably the best novel yet produced by an American woman" and named it, along with Uncle Tom's Cabin, one of two most ethical novels of the 19th century.